SCHEMBL17367108

SCHEMBL17367108

c1ccc2cc(-c3ccc4cc(-n5c6ccccc6c6ccc7c(sc8sc9ccccc9c87)c65)ccc4c3)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PMM2 O15305 1/20 0.35
MPI P34949 1/20 0.35
PHOSPHO1 Q8TCT1 1/20 0.35
RPA1 P27694 1/20 0.33
S1PR4 O95977 2/20 0.32
S1PR5 Q9H228 2/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32
TUBB2B Q9BVA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17367105 0.96 PMM2 (0.38) PMM2MPIPHOSPHO1HPGD
SCHEMBL17367092 0.91 S1PR5 (0.38) PMM2MPIPHOSPHO1S1PR4S1PR5
SCHEMBL17366943 0.87 PMM2 (0.36) PMM2MPIPHOSPHO1RPA1S1PR4
SCHEMBL17367127 0.84 PMM2 (0.38) PMM2MPIPHOSPHO1HPGD
SCHEMBL10014562 0.84 PMM2 (0.41) PMM2MPIPHOSPHO1HPGD
SCHEMBL19653113 0.83 PMM2 (0.36) PMM2MPIPHOSPHO1RPA1S1PR4
SCHEMBL24676237 0.83 KDM4E (0.36) PMM2MPIPHOSPHO1
SCHEMBL17367095 0.83 ATM (0.36)
SCHEMBL18086225 0.82 HSD17B1 (0.37) PMM2MPIPHOSPHO1RPA1S1PR4
SCHEMBL17246412 0.82 ESR1 (0.34) PMM2MPIPHOSPHO1RPA1S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, CRY1, CYP1B1 PMM2 4227/4885MPI 3400/4885PHOSPHO1 4069/4885
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same CYP1A1, CRY1, CYP1B1 PMM2 4227/4885MPI 3400/4885PHOSPHO1 4069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.