SCHEMBL17367116

SCHEMBL17367116

c1ccc(-n2c3ccccc3c3c4ccc5c6ccccc6n(-c6cccc(-c7cccc8ccccc78)c6)c5c4sc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
MAPT P10636 2/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAPK14 Q16539 1/20 0.31
FLT3 P36888 1/20 0.31
BMX P51813 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17367111 0.92 S1PR5 (0.36) L3MBTL1KDM4EATMCYP1A1CYP1B1
SCHEMBL17367049 0.90 L3MBTL1 (0.39) L3MBTL1KDM4EATMCYP1A1CYP1B1
SCHEMBL17367110 0.89 L3MBTL1 (0.41) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL25775169 0.86 L3MBTL1 (0.46) L3MBTL1KDM4EATMMCL1ACMSD
SCHEMBL17367006 0.86 L3MBTL1 (0.37) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL25775227 0.84 L3MBTL1 (0.43) L3MBTL1KDM4EATMMCL1ACMSD
SCHEMBL17366895 0.84 FLT3 (0.32) KDM4EMAPTFLT3BMXALDH1A1
SCHEMBL23600377 0.84 L3MBTL1 (0.44) L3MBTL1KDM4EATMMCL1ACMSD
SCHEMBL21152038 0.84 L3MBTL1 (0.46) L3MBTL1KDM4EATMMCL1ACMSD
SCHEMBL17367129 0.83 L3MBTL1 (0.52) L3MBTL1KDM4EATMMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, CRY1, CYP1B1 L3MBTL1 717/4885KDM4E 3404/4885ATM 3202/4885
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same CYP1A1, CRY1, CYP1B1 L3MBTL1 717/4885KDM4E 3404/4885ATM 3202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.