SCHEMBL17367608

SCHEMBL17367608

C=CCN(CC=C)C(=O)c1cccc(Oc2cccc(C(=O)N(CC=C)CC=C)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.54
ALDH1A1 P00352 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
AKR1C3 P42330 1/20 0.47
TNKS O95271 1/20 0.44
PARP15 Q460N3 1/20 0.44
PARP14 Q460N5 1/20 0.44
PARP10 Q53GL7 1/20 0.44
TNKS2 Q9H2K2 1/20 0.44
PARP2 Q9UGN5 1/20 0.44
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
TSHR P16473 2/20 0.42
KMO O15229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL176463 0.87 POLB (0.48) POLBALDH1A1TDP1MEN1KMT2A
SCHEMBL13133194 0.87 POLB (0.54) POLBALDH1A1TDP1KDM4EMEN1
SCHEMBL13133149 0.85 POLB (0.53) POLBALDH1A1TDP1MEN1KMT2A
SCHEMBL11872290 0.79 HPGD (0.66) POLBALDH1A1TDP1MEN1KMT2A
SCHEMBL8852218 0.79 POLB (0.46) POLBALDH1A1TDP1MEN1KMT2A
SCHEMBL1594537 0.79 POLB (0.46) POLBALDH1A1TDP1MEN1KMT2A
SCHEMBL176484 0.78 TSHR (0.53) POLBALDH1A1KDM4EMEN1KMT2A
SCHEMBL31517047 0.76 HPGD (0.56) ALDH1A1TDP1KDM4EMEN1KMT2A
SCHEMBL176438 0.75 MEN1 (0.47) POLBALDH1A1TDP1KDM4EMEN1
SCHEMBL10051083 0.75 ALDH1A1 (0.45) POLBALDH1A1TDP1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150376453-A1 ORGANIC POLYSILOXANE COMPOSITION, ENCAPSULANT, AND ELECTRONIC DEVICE SAMSUNG SDI CO., LTD. (KR) 2015-12-31 US disclosed
US-20150376453-A1 ORGANIC POLYSILOXANE COMPOSITION, ENCAPSULANT, AND ELECTRONIC DEVICE SAMSUNG SDI CO., LTD. (KR) 2015-12-31 US disclosed