Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26493009 | 0.89 | GRIK1 (0.57) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL17302563 | 0.86 | GPR84 (0.66) | GRIK1GRIK2GPR84FFAR1FFAR4 | |
| SCHEMBL17294505 | 0.86 | GPR84 (0.66) | GRIK1GRIK2GPR84FFAR1FFAR4 | |
| SCHEMBL17368067 | 0.86 | L3MBTL1 (0.47) | GRIK1GRIK2GPR84NOD1FFAR1 | |
| SCHEMBL17368080 | 0.86 | L3MBTL1 (0.47) | GRIK1GRIK2GPR84NOD1FFAR1 | |
| SCHEMBL17368070 | 0.86 | L3MBTL1 (0.47) | GRIK1GRIK2GPR84NOD1FFAR1 | |
| SCHEMBL3524848 | 0.85 | FFAR1 (0.61) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL17199810 | 0.85 | GPR84 (0.47) | GPR84FFAR1FFAR4PLA2G1BPLA2G2A | |
| SCHEMBL29138696 | 0.83 | FFAR4 (0.70) | GPR84FFAR1FFAR4 | |
| SCHEMBL7854619 | 0.83 | FFAR4 (0.70) | GPR84FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659003-B | Berberine derivative and preparation method and application thereof | 西南大学 | 2024-11-26 | — | — | CN | disclosed |
| CN-117659003-A | Berberine derivative and preparation method and application thereof | 西南大学 | 2024-03-08 | — | — | CN | disclosed |
| US-20150376144-A1 | STEREOCHEMICALLY ENRICHED COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO, INC. | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376144-A1 | STEREOCHEMICALLY ENRICHED COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS | POLB, SNRPB2, HNRNPA2B1 | GRIK1 3787/4885GRIK2 3950/4885SLC1A2 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.