Gingerol

Gingerol

SCHEMBL17368634

CCCCC[C@@H](O)CC(=O)CCc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 1.00
CYP3A4 P08684 5/20 1.00
TRPV1 Q8NER1 5/20 1.00
CYP2C8 P10632 4/20 1.00
CYP2C9 P11712 4/20 1.00
CYP2B6 P20813 4/20 1.00
CYP2C19 P33261 4/20 1.00
CYP1A2 P05177 3/20 1.00
HTR1A P08908 3/20 0.98
CYP2D6 P10635 2/20 0.98
CYP2A6 P11509 2/20 0.98
CYP2E1 P05181 1/20 0.98
POLB P06746 1/20 0.72
GAA P10253 1/20 0.72
ALOX5 P09917 1/20 0.61
OR51E2 Q9H255 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gingerol SCHEMBL2121898 1.00 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
Gingerol SCHEMBL32102 1.00 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
Gingerol SCHEMBL30767163 1.00 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
Gingerol SCHEMBL29475335 1.00 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL17301613 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL20668234 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL17301612 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL20668179 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL4883453 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL4885722 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104159-A1 CALCIUM CHANNEL BLOCKER AND SCREENING METHOD THEREOF XIE MINGQI (CN) 2023-06-15 WO disclosed
US-11540539-B2 Reduced sodium food products GENERAL MILLS, INC. (US) 2023-01-03 US disclosed
EP-3732994-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2022-11-09 EP disclosed
EP-3366677-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2020-09-09 EP disclosed
EP-2954037-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2018-04-11 EP disclosed
US-20150374021-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. 2015-12-31 US disclosed
US-20150374021-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. 2015-12-31 US disclosed