Gingerol

Gingerol

SCHEMBL29475335

CCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 6/20 1.00
▸ CYP3A4 P08684 5/20 1.00
▸ TRPV1 Q8NER1 5/20 1.00
▸ CYP2C8 P10632 4/20 1.00
▸ CYP2C9 P11712 4/20 1.00
▸ CYP2B6 P20813 4/20 1.00
▸ CYP2C19 P33261 4/20 1.00
▸ CYP1A2 P05177 3/20 1.00
▸ HTR1A P08908 3/20 0.98
▸ CYP2D6 P10635 2/20 0.98
▸ CYP2A6 P11509 2/20 0.98
▸ CYP2E1 P05181 1/20 0.98
▸ POLB P06746 1/20 0.72
▸ GAA P10253 1/20 0.72
▸ ALOX5 P09917 1/20 0.61
▸ OR51E2 Q9H255 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gingerol SCHEMBL2121898 1.00 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
Gingerol SCHEMBL17368634 1.00 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
Gingerol SCHEMBL30767163 1.00 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
Gingerol SCHEMBL32102 1.00 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL4883453 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL20668234 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL17301613 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL20668179 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL17301612 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9
SCHEMBL4885722 0.99 LTA4H (1.00) LTA4HCYP3A4TRPV1CYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023031860-A1 COMPOSITIONS, KITS, AND METHODS TO PROVIDE SYNERGISTIC AND/OR ADDITIVE EFFECTS FROM COMPRISED INGREDIENTS FOR THE PREVENTION, TREATMENT AND MANAGEMENT OF NAUSEA AND VOMITING. PATEL, Natvarlal Hargovinddas (IN) 2023-03-09 — — WO claimed
WO-2023031861-A1 COMPOSITIONS, KITS, AND METHODS FOR TREATMENT OF NAUSEA AND VOMITING PATEL, Natvarlal Hargovinddas (IN) 2023-03-09 — — WO claimed
WO-2023031779-A1 COMPOSITIONS, KITS, AND METHODS TO PROVIDE SYNERGISTIC AND/OR ADDITIVE EFFECTS FROM COMPRISED INGREDIENTS FOR THE PREVENTION, TREATMENT AND MANAGEMENT OF NAUSEA AND VOMITING PATEL, Natvarlal Hargovinddas (IN) 2023-03-09 — — WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
US-12590115-B2 Technologies useful for oligonucleotide preparation WAVE LIFE SCIENCES LTD. (SG) 2026-03-31 — — US disclosed
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD (SG) 2026-02-26 — — US disclosed
EP-4680210-A1 MEDICAL PATCH COMPRISING SKIN IRRITATING ACTIVE AGENT LTS Lohmann Therapie-Systeme AG (DE) 2026-01-21 — — EP disclosed
US-20260008806-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD (SG) 2026-01-08 — — US disclosed
US-12435105-B2 Technologies for oligonucleotide preparation WAVE LIFE SCIENCES LTD. (SG) 2025-10-07 — — US disclosed
WO-2025202300-A1 COMPLEX COACERVATES FOR NUTRACEUTICALS NEKTIUM PHARMA S.L. (ES) 2025-10-02 — — WO disclosed
EP-4623703-A1 COMPLEX COACERVATES FOR NUTRACEUTICALS Nektium Pharma S.L. (ES) 2025-10-01 — — EP disclosed
US-12428442-B2 Compounds, compositions and methods for synthesis WAVE LIFE SCIENCES LTD. (SG) 2025-09-30 — — US disclosed
US-11541019-B2 Compositions for use in the treatment of diabetes UNIVERSITY OF ULSTER (GB) 2023-01-03 — — US disclosed
WO-2022238249-A2 PROCESS OF MAKING GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH SA (CH) 2022-11-17 — — WO disclosed
US-20220356204-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD. (SG) 2022-11-10 — — US disclosed
CN-110087664-B Compositions and methods for treating orthopedic disorders K.L.R.M.有限公司 2022-11-01 — — CN disclosed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO disclosed
CN-114727646-A Novel aerosol-generating substrate comprising ginger species 菲利普莫里斯生产公司 2022-07-08 — — CN disclosed
CN-109923469-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2022-06-28 — — CN disclosed
EP-3328199-B1 ANTIMICROBIAL COMPOSITIONS AND USES THEREOF NOVUS INT INC (US) 2022-03-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008806-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION RNGTT, RNMT, NSUN2 LTA4H 1630/4885CYP3A4 4297/4885TRPV1 4658/4885
US-20220356204-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS ALKBH1, DUT, RNGTT LTA4H 2972/4885CYP3A4 3582/4885TRPV1 4045/4885
US-12435105-B2 Technologies for oligonucleotide preparation POLRMT, DCLRE1B, RNGTT LTA4H 3440/4885CYP3A4 4195/4885TRPV1 4776/4885
US-12428442-B2 Compounds, compositions and methods for synthesis ALKBH1, DUT, RNGTT LTA4H 2972/4885CYP3A4 3582/4885TRPV1 4045/4885
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS NSUN2, NSUN3, NOP2 LTA4H 3608/4885CYP3A4 3621/4885TRPV1 4198/4885
US-12590115-B2 Technologies useful for oligonucleotide preparation NOP2, RNGTT, NSUN2 LTA4H 2891/4885CYP3A4 4254/4885TRPV1 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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