Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736072 | 0.99 | DYRK1A (0.40) | DYRK1ARAB9ANPC1KMT2AMAPT | |
| SCHEMBL1737404 | 0.91 | DYRK1A (0.40) | DYRK1ARAB9ANPC1MAPTTP53 | |
| SCHEMBL1736053 | 0.90 | DYRK1A (0.40) | DYRK1ARAB9ANPC1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1737655 | 0.90 | DYRK1A (0.40) | DYRK1ARAB9ANPC1MAPTTP53 | |
| SCHEMBL1739295 | 0.90 | RAB9A (0.45) | DYRK1ARAB9ANPC1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL1739792 | 0.89 | DYRK1A (0.39) | DYRK1ARAB9ANPC1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1737677 | 0.89 | RAB9A (0.44) | DYRK1ARAB9ANPC1KMT2AMAPT | |
| SCHEMBL1737062 | 0.88 | RAB9A (0.49) | RAB9ANPC1KMT2AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL1736429 | 0.87 | RAB9A (0.48) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL1737594 | 0.85 | HRH3 (0.41) | DYRK1ARAB9ANPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |