Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1737655 | 0.99 | DYRK1A (0.40) | DYRK1ANPC1RAB9AMAOAMAOB | |
| SCHEMBL1737044 | 0.91 | DYRK1A (0.41) | DYRK1ANPC1RAB9AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1736072 | 0.90 | DYRK1A (0.40) | DYRK1ANPC1RAB9AALDH1A1TP53 | |
| SCHEMBL1737253 | 0.90 | DYRK1A (0.38) | DYRK1ANPC1RAB9AMAOAMAOB | |
| SCHEMBL1736053 | 0.89 | DYRK1A (0.40) | DYRK1ANPC1RAB9AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL1736373 | 0.89 | DYRK1A (0.38) | DYRK1ANPC1RAB9AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL1739792 | 0.88 | DYRK1A (0.39) | DYRK1ANPC1RAB9AMAOAMAOB | |
| SCHEMBL1739067 | 0.88 | RAB9A (0.41) | NPC1RAB9AMAOAMAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL1736057 | 0.87 | RAB9A (0.40) | NPC1RAB9AMAOAMAOBALDH1A1 | |
| SCHEMBL1736156 | 0.85 | MAPT (0.42) | DYRK1AMAOBTP53MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |