SCHEMBL1737057

SCHEMBL1737057

C=CCn1c(C)c(C)c2ccnc(COc3ccc(F)cc3F)c21

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.36
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
TRPA1 O75762 6/20 0.35
RAB9A P51151 4/20 0.35
PKM P14618 1/20 0.34
HASPIN Q8TF76 1/20 0.33
NPC1 O15118 3/20 0.33
NMT2 O60551 1/20 0.33
NMT1 P30419 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1737686 0.99 FFAR1 (0.36) FFAR1ALDH1A1MEN1KMT2APOLB
SCHEMBL1738301 0.88 RAB9A (0.36) FFAR1ALDH1A1MEN1KMT2APOLB
SCHEMBL1737252 0.87 RAB9A (0.39) FFAR1ALDH1A1MEN1KMT2APOLB
Hydrochloric Acid SCHEMBL1737633 0.87 RAB9A (0.35) FFAR1ALDH1A1MEN1KMT2APOLB
Hydrochloric Acid SCHEMBL1736956 0.86 RAB9A (0.38) FFAR1ALDH1A1MEN1KMT2APOLB
SCHEMBL1736996 0.85 RAB9A (0.38) FFAR1ALDH1A1MEN1KMT2APOLB
SCHEMBL1737110 0.84 NPC1 (0.38) ALDH1A1POLBRAB9ANPC1L3MBTL1
Hydrochloric Acid SCHEMBL1737972 0.84 RAB9A (0.37) FFAR1ALDH1A1MEN1KMT2APOLB
SCHEMBL1736802 0.84 L3MBTL1 (0.39) FFAR1MEN1KMT2ATRPA1RAB9A
SCHEMBL1737096 0.84 L3MBTL1 (0.36) KMT2AHPGDRAB9APKMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-A4 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-09-09 EP disclosed
EP-1784404-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 EP disclosed
WO-2006025716-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed