Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1737673 | 0.99 | TP53 (0.44) | TP53TDP1RECQLMAPTPPARG | |
| SCHEMBL1737378 | 0.92 | NPC1 (0.39) | TP53TDP1RECQLMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1736376 | 0.91 | SMN1; SMN2 (0.39) | TP53TDP1RECQLMAPTSMN1; SMN2 | |
| SCHEMBL1735942 | 0.87 | DYRK1A (0.47) | TP53TDP1RECQLMAPTADAMTS5 | |
| Hydrochloric Acid SCHEMBL1736539 | 0.86 | DYRK1A (0.47) | TP53TDP1RECQLMAPTADAMTS5 | |
| SCHEMBL1738711 | 0.84 | MAPT (0.41) | TP53MAPTPPARGADAMTS5KDM4E | |
| Hydrochloric Acid SCHEMBL1736702 | 0.83 | MAPT (0.40) | TP53MAPTPPARGADAMTS5DYRK1A | |
| SCHEMBL1736377 | 0.83 | MAPT (0.41) | TP53MAPTADAMTS5KDM4EDYRK1A | |
| SCHEMBL1737387 | 0.83 | MAPT (0.41) | TP53MAPTADAMTS5KDM4EDYRK1A | |
| SCHEMBL1737349 | 0.82 | DYRK1A (0.38) | TP53TDP1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |