Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | AGER | Q15109 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737254 | 0.90 | BRD4 (0.61) | ALDH1A1L3MBTL1TSHRHTTBRD4 | |
| SCHEMBL29870373 | 0.90 | BRD4 (0.61) | ALDH1A1L3MBTL1TSHRHTTBRD4 | |
| SCHEMBL27492813 | 0.88 | ALDH1A1 (0.60) | ALDH1A1KDM4EALOX15L3MBTL1TSHR | |
| SCHEMBL31037820 | 0.87 | KDM4E (0.61) | ALDH1A1KDM4EALOX15L3MBTL1TSHR | |
| SCHEMBL14840493 | 0.87 | TSHR (0.58) | ALDH1A1L3MBTL1TSHRMAPTHTT | |
| SCHEMBL4914014 | 0.87 | KDM4E (0.61) | ALDH1A1KDM4EALOX15L3MBTL1TSHR | |
| SCHEMBL14840457 | 0.84 | TSHR (0.54) | ALDH1A1L3MBTL1TSHRHTTBRD4 | |
| SCHEMBL2801546 | 0.84 | BRD4 (0.56) | ALDH1A1KDM4EL3MBTL1TSHRMAPT | |
| SCHEMBL21639387 | 0.83 | TSHR (0.53) | ALDH1A1L3MBTL1TSHRHTTBRD4 | |
| SCHEMBL8616148 | 0.83 | TSHR (0.53) | ALDH1A1L3MBTL1TSHRHTTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384714-A | The recovery method and production method of substituted or unsubstituted 2,3- pyridinedicarboxylic acid | 北京颖泰嘉和生物科技股份有限公司 | 2019-02-26 | — | — | CN | claimed |
| EP-1087953-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 2001-04-04 | — | — | EP | claimed |
| WO-1999067231-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 1999-12-29 | — | — | WO | claimed |
| WO-2024060966-A1 | PAN-KRAS INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2024-03-28 | — | — | WO | disclosed |
| US-20200392492-A1 | Modulating Immune Responses | UNIVERSITY OF MIAMI | 2020-12-17 | — | — | US | disclosed |
| CN-109384714-A | The recovery method and production method of substituted or unsubstituted 2,3- pyridinedicarboxylic acid | 北京颖泰嘉和生物科技股份有限公司 | 2019-02-26 | — | — | CN | disclosed |
| EP-1087953-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999067231-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 1999-12-29 | — | — | WO | disclosed |
| EP-0576433-A1 | USE OF LACIDIPINE FOR THE TREATMENT OF ARTERIOSCLEROSIS | GLAXO S.p.A. (IT) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992014460-A1 | USE OF LACIDIPINE FOR THE TREATMENT OF ARTERIOSCLEROSIS | GLAXO SPA (IT) | 1992-09-03 | — | — | WO | disclosed |