Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18524415 | 0.76 | — | — | |
| SCHEMBL30450485 | 0.68 | HPGD (0.30) | — | |
| SCHEMBL30491342 | 0.66 | — | — | |
| SCHEMBL28624271 | 0.64 | ALDH1A1 (0.37) | — | |
| SCHEMBL15055780 | 0.62 | — | — | |
| SCHEMBL18524116 | 0.62 | — | — | |
| SCHEMBL1446038 | 0.61 | CYP3A4 (0.59) | — | |
| SCHEMBL30336974 | 0.61 | HSD17B10 (0.42) | — | |
| SCHEMBL11208796 | 0.60 | HTR2A (0.36) | PNMT | |
| SCHEMBL15056458 | 0.59 | KDM4E (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157915-A1 | SUBSTITUTED DIHYDROISOQUINOLINONE COMPOUNDS | Pfizer Inc. (US) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015193765-A1 | SUBSTITUTED DIHYDROISOQUINOLINONE COMPOUNDS | PFIZER INC. (US) | 2015-12-23 | — | — | WO | disclosed |