Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904746 | 1.00 | CES2 (0.55) | CES2CHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL11395919 | 1.00 | CES2 (0.55) | CES2CHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL27752426 | 1.00 | CES2 (0.55) | CES2CHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL32676262 | 0.98 | DPP7 (0.53) | CES2CHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL6271110 | 0.93 | GNAI3 (0.64) | CES2CHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL32676289 | 0.93 | GNAI3 (0.64) | CES2CHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL5319167 | 0.92 | CES2 (0.55) | CES2CHRM2CHRM4CHRM1DPP7 | |
| SCHEMBL25469804 | 0.90 | GNAI3 (0.57) | CES2CHRM2CHRM4CHRM1GNAI3 | |
| Bromide SCHEMBL5269921 | 0.90 | CES2 (0.53) | CES2CHRM2CHRM4CHRM1DPP7 | |
| SCHEMBL12134906 | 0.89 | CES2 (0.52) | CES2CHRM2CHRM4CHRM1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160938-A1 | NOVEL LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | Acuitas Therapeutics Inc. (CA) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015199952-A1 | NOVEL LIPIDS AND LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS | ACUITAS THERAPEUTICS INC. (CA) | 2015-12-30 | — | — | WO | disclosed |