SCHEMBL1737486

SCHEMBL1737486

C=CCn1c(C)c(C)c2ccnc(-c3ccc(C=C)cc3)c21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CACNA1B Q00975 1/20 0.34
RAB9A P51151 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 3/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
TNNI3 P19429 1/20 0.31
TNNT2 P45379 1/20 0.31
TNNC1 P63316 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1736147 0.99 CACNA1B (0.34) CACNA1BRAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL1735921 0.90 NPSR1 (0.41) RAB9ACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1737960 0.89 CACNA1B (0.35) CACNA1BMAPTKMT2AMEN1TP53
Hydrochloric Acid SCHEMBL1736632 0.89 NPSR1 (0.40) RAB9ACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1737073 0.88 CACNA1B (0.32) CACNA1B
Hydrochloric Acid SCHEMBL1736808 0.88 CACNA1B (0.34) CACNA1B
SCHEMBL1738539 0.88 ALDH1A1 (0.41) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL1739802 0.88 MAPT (0.42) RAB9ACYP1A2CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL1738437 0.87 CACNA1B (0.32) CACNA1B
SCHEMBL1738045 0.87 L3MBTL1 (0.40) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed