Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17379065 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL1789117 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL22140424 | 0.80 | NR1H4 (0.53) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17923907 | 0.78 | ATM (0.53) | ALDH1A1TSHRKDM4EGAAALOX15 | |
| SCHEMBL4089116 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2791258 | 0.77 | KDM4E (0.42) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17375003 | 0.77 | KMT2A (0.45) | LMNAMEN1KMT2AABCB11CYP1A2 | |
| SCHEMBL10399132 | 0.77 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18748269 | 0.76 | TSHR (0.45) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24453339 | 0.76 | PPARG (0.48) | MEN1KMT2ASMN1; SMN2CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |