Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640552 | 0.80 | CYP3A4 (0.47) | KMT2AMEN1POLBCYP3A4NR1H4 | |
| SCHEMBL17375002 | 0.77 | ALDH1A1 (0.42) | KMT2AMEN1L3MBTL1ABCB11CYP1A2 | |
| SCHEMBL13762179 | 0.76 | NQO1 (0.46) | KMT2AMEN1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL6451238 | 0.75 | ALDH1A1 (0.55) | KMT2AMEN1L3MBTL1POLBTSHR | |
| SCHEMBL6891211 | 0.74 | MAPT (0.51) | KMT2AMEN1L3MBTL1NR1H4NPSR1 | |
| SCHEMBL1808069 | 0.74 | ABCB11 (0.56) | KMT2AMEN1ABCB11CYP1A2CYP3A4 | |
| SCHEMBL11234025 | 0.73 | MAPT (0.38) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL3930793 | 0.73 | MCL1 (0.60) | KMT2AMEN1L3MBTL1TSHRKDM4E | |
| SCHEMBL8421941 | 0.73 | KMT2A (0.56) | KMT2AMEN1L3MBTL1POLBCA2 | |
| SCHEMBL15496627 | 0.72 | HPGD (0.54) | KMT2AL3MBTL1POLBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |