⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18093520 | 0.64 | KDM4E (0.48) | — | |
| SCHEMBL11063868 | 0.63 | — | — | |
| SCHEMBL1735272 | 0.63 | — | — | |
| SCHEMBL864865 | 0.63 | — | — | |
| SCHEMBL11713219 | 0.62 | LMNA (0.43) | — | |
| SCHEMBL1238024 | 0.60 | — | — | |
| 2-Picolinic Acid SCHEMBL15271681 | 0.60 | CES2 (0.64) | — | |
| 2-Picolinic Acid SCHEMBL28759277 | 0.60 | CES2 (0.64) | — | |
| Hydrochloric Acid SCHEMBL9958495 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL9956689 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521289-B1 | MNK INHIBITORS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS INC (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-3521289-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | Effector Therapeutics Inc. (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-3160966-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | Effector Therapeutics Inc. (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015200481-A1 | MNK INHIBITORS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS, INC. (US) | 2015-12-30 | — | — | WO | disclosed |