Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12027408 | 0.92 | IDO1 (0.46) | MEN1KMT2ALMNASMN1; SMN2IDO1 | |
| SCHEMBL84956 | 0.92 | IDO1 (0.46) | MEN1KMT2ALMNASMN1; SMN2IDO1 | |
| Hydrogen Peroxide SCHEMBL8580007 | 0.86 | MEN1 (0.47) | MEN1KMT2ALMNASMN1; SMN2IDO1 | |
| SCHEMBL2662627 | 0.84 | CYP17A1 (0.47) | MEN1KMT2ALMNASMN1; SMN2IDO1 | |
| SCHEMBL19440255 | 0.83 | MEN1 (0.50) | MEN1KMT2ALMNAIDO1TDO2 | |
| SCHEMBL10805932 | 0.80 | ESR1 (0.54) | MEN1KMT2ALMNATYRHTT | |
| SCHEMBL12591802 | 0.78 | NFKB1 (0.50) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8303307 | 0.78 | SOS1 (0.44) | MEN1KMT2AIDO1TDO2ALDH1A1 | |
| SCHEMBL18589839 | 0.78 | NFE2L2 (0.58) | TYR | |
| SCHEMBL23621914 | 0.78 | ESR1 (0.57) | MEN1KMT2ALMNASMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197096-A1 | PREPARATION AND MEDICAL USE OF TRIAZENES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2015-12-30 | — | — | WO | disclosed |