Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.56 |
| ▸ | CXCR3 | P49682 | 9/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17458368 | 0.83 | PIK3CD (0.66) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL17458370 | 0.83 | PIK3CD (0.66) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL17458210 | 0.79 | PIK3CD (0.69) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL23912254 | 0.76 | PIK3CD (0.55) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL15813008 | 0.75 | PIK3CD (0.54) | PIK3CDCXCR3HDAC6PIK3CBPIK3CG | |
| SCHEMBL15813010 | 0.75 | PIK3CD (0.54) | PIK3CDCXCR3HDAC6PIK3CBPIK3CG | |
| SCHEMBL17458227 | 0.75 | PIK3CD (0.64) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL17458224 | 0.75 | PIK3CD (0.64) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL17461939 | 0.74 | PIK3CD (0.62) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL8437614 | 0.72 | CXCR3 (0.65) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015200352-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-30 | — | — | WO | disclosed |