Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20404284 | 0.83 | SMN1; SMN2 (0.48) | PIK3CDHDAC6SMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL17458370 | 0.83 | PIK3CD (0.66) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL17458368 | 0.83 | PIK3CD (0.66) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL23912253 | 0.82 | SMN1; SMN2 (0.45) | PIK3CDHDAC6SMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL17458210 | 0.81 | PIK3CD (0.69) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA | |
| SCHEMBL15817874 | 0.79 | PIK3CD (0.49) | PIK3CDSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL17235505 | 0.78 | ESR1 (0.60) | HDAC6SMN1; SMN2ALDH1A1ESR1ESR2 | |
| SCHEMBL20404396 | 0.78 | PIK3CD (0.57) | PIK3CDPIK3CGSMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL23912237 | 0.78 | HRH3 (0.59) | PIK3CD | |
| SCHEMBL17375329 | 0.76 | PIK3CD (0.56) | PIK3CDHDAC6PIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |