Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19260705 | 0.92 | HTR4 (0.56) | HTR4ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL17375500 | 0.89 | KDM4E (0.58) | HTR4ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL30764768 | 0.89 | KDM4E (0.58) | HTR4ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL2235600 | 0.83 | KDM4E (0.56) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2926517 | 0.82 | HTR4 (0.56) | HTR4ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL18089590 | 0.82 | KDM4E (0.54) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL19260656 | 0.81 | KDM4E (0.59) | HTR4ALDH1A1MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL2925147 | 0.81 | HTR4 (0.57) | HTR4ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4379114 | 0.80 | HTR4 (0.60) | HTR4ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL13299069 | 0.79 | KDM4E (0.51) | ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015198249-A1 | PROCESS FOR PREPARATION OF BOSUTINIB | SHILPA MEDICARE LIMITED (IN) | 2015-12-30 | — | — | WO | disclosed |