Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Cyclopropanecarboximidamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropanecarboximidamide SCHEMBL1221622 | 0.93 | — | — | |
| SCHEMBL9705757 | 0.93 | NOS2 (1.00) | — | |
| SCHEMBL9705753 | 0.93 | NOS2 (1.00) | — | |
| Hydrochloric Acid SCHEMBL9292761 | 0.90 | NOS2 (0.93) | — | |
| Cyclopropanecarboximidamide SCHEMBL275450 | 0.90 | — | — | |
| Cyclopropanecarboximidamide SCHEMBL25215941 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL9292759 | 0.90 | NOS2 (0.93) | — | |
| SCHEMBL20041277 | 0.81 | NOS2 (0.77) | — | |
| Cyclopropanecarboximidamide SCHEMBL6621298 | 0.81 | NOS2 (0.77) | — | |
| SCHEMBL11568588 | 0.81 | NOS2 (0.77) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604118-A | Perovskite solar cell | 华南师范大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-106488919-B | 3-substituted 2-aminoindole derivatives | 武田药品工业株式会社 | 2018-10-23 | — | — | CN | disclosed |
| US-10059713-B2 | 3-substituted 2-amino-indole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-08-28 | — | — | US | disclosed |
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |
| US-20170158700-A1 | 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES | TAKEDA CAMBRIDGE LIMITED (GB) | 2017-06-08 | — | — | US | disclosed |
| EP-3160965-A1 | 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2017-05-03 | — | — | EP | disclosed |
| CN-106488919-A | 3-substituted 2-aminoindole derivatives | 武田药品工业株式会社 | 2017-03-08 | — | — | CN | disclosed |
| WO-2015198045-A1 | 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-12-30 | — | — | WO | disclosed |