Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17376700 | 1.00 | NR3C1 (0.32) | NR3C1CYP3A4TNFSF11MAPTKMT2A | |
| SCHEMBL31266411 | 0.92 | ACACB (0.30) | ACACB | |
| SCHEMBL30665975 | 0.91 | ACACB (0.33) | CYP3A4MAPTKMT2AMEN1LMNA | |
| SCHEMBL30643891 | 0.91 | ACACB (0.33) | CYP3A4MAPTKMT2AMEN1LMNA | |
| SCHEMBL17381878 | 0.91 | ACACB (0.33) | CYP3A4MAPTKMT2AMEN1LMNA | |
| SCHEMBL17376698 | 0.90 | GNG2 (0.30) | — | |
| SCHEMBL17376699 | 0.90 | GNG2 (0.30) | — | |
| SCHEMBL17382606 | 0.89 | FGFR1 (0.33) | ACACB | |
| SCHEMBL17381881 | 0.89 | FGFR1 (0.33) | ACACB | |
| SCHEMBL17381884 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662138-B2 | Herbicidal propynyl-phenyl compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| EP-3160950-B1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |
| US-20170183281-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-29 | — | — | US | disclosed |
| EP-3160950-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | Syngenta Participations AG (CH) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015197468-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662138-B2 | Herbicidal propynyl-phenyl compounds | CBR3, CBR1, CNPY3 | NR3C1 509/4885CYP3A4 1450/4885TNFSF11 4723/4885 |
| US-20170183281-A1 | HERBICIDAL PROPYNYL-PHENYL COMPOUNDS | CBR3, CBR1, CNPY3 | NR3C1 509/4885CYP3A4 1450/4885TNFSF11 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.