Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737126 | 1.00 | TP53 (0.47) | TP53ALDH1A1MAPTCLK4MEN1 | |
| Hydrochloric Acid SCHEMBL1737366 | 0.99 | TP53 (0.47) | TP53ALDH1A1MAPTCLK4MEN1 | |
| Hydrochloric Acid SCHEMBL1737958 | 0.99 | TP53 (0.47) | TP53ALDH1A1MAPTCLK4MEN1 | |
| SCHEMBL1739797 | 0.95 | ALDH1A1 (0.46) | TP53ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1735548 | 0.94 | ALDH1A1 (0.44) | TP53ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1737422 | 0.92 | LMNA (0.46) | TP53ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1738530 | 0.92 | KDM4E (0.46) | ALDH1A1MAPTMEN1KMT2ACLK1 | |
| Hydrochloric Acid SCHEMBL1736621 | 0.91 | LMNA (0.46) | TP53ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1736616 | 0.91 | KDM4E (0.44) | ALDH1A1MAPTMEN1KMT2ACLK1 | |
| SCHEMBL1738913 | 0.90 | ALDH1A1 (0.47) | TP53ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |