Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.48 |
| ▸ | KDM6B | O15054 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587140 | 0.86 | KDM4C (0.50) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL29900258 | 0.83 | KDM4E (0.57) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL31522172 | 0.79 | NR4A1 (0.60) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL2223329 | 0.79 | NR4A1 (0.60) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL30694782 | 0.79 | ALDH1A1 (0.54) | KDM4EALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL2149297 | 0.78 | NR4A1 (0.59) | KDM4EALDH1A1MEN1KMT2ASLC22A12 | |
| SCHEMBL30430793 | 0.78 | NR4A1 (0.59) | KDM4EALDH1A1MEN1KMT2ASLC22A12 | |
| Hydrochloric Acid SCHEMBL29816682 | 0.78 | NR4A1 (0.58) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| SCHEMBL30771576 | 0.78 | NR4A1 (0.58) | KDM4CKDM6BKDM4EKDM4DTDP1 | |
| Hydrochloric Acid SCHEMBL4617820 | 0.77 | NR4A1 (0.57) | KDM4EALDH1A1MEN1KMT2ASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301752-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2024-01-10 | — | — | EP | disclosed |
| CN-117295736-A | Benzo [ C ] [2,6] naphthyridine derivatives, compositions thereof and therapeutic uses thereof | 剑桥实业有限公司 | 2023-12-26 | — | — | CN | disclosed |
| WO-2022185041-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2022-09-09 | — | — | WO | disclosed |
| WO-2015199503-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING DEGENERATIVE BRAIN DISEASES, CONTAINING CX-4945 AS ACTIVE INGREDIENT | 한국생명공학연구원 | 2015-12-30 | — | — | WO | disclosed |