Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 2/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430793 | 1.00 | NR4A1 (0.59) | NR4A1NR4A2NR4A3CDC25BWDR5 | |
| Hydrochloric Acid SCHEMBL4617820 | 0.98 | NR4A1 (0.57) | NR4A1NR4A2NR4A3CDC25BWDR5 | |
| SCHEMBL7374228 | 0.86 | CDC25B (0.48) | NR4A1NR4A2NR4A3CDC25BWDR5 | |
| Bromide SCHEMBL7369447 | 0.84 | CDC25B (0.47) | NR4A1NR4A2NR4A3CDC25BMEN1 | |
| SCHEMBL5047448 | 0.83 | AKR1C3 (0.46) | NR4A1NR4A2NR4A3CDC25BALDH1A1 | |
| SCHEMBL30032983 | 0.83 | AKR1C3 (0.46) | NR4A1NR4A2NR4A3CDC25BALDH1A1 | |
| SCHEMBL8966381 | 0.82 | CYP11B1 (0.43) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL30241191 | 0.82 | KDM4E (0.50) | NR4A1NR4A2NR4A3ALDH1A1KDM4E | |
| SCHEMBL7067803 | 0.82 | NR4A1 (0.42) | NR4A1NR4A2NR4A3CDC25BALDH1A1 | |
| SCHEMBL1121657 | 0.82 | KDM4E (0.50) | NR4A1NR4A2NR4A3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286572-B | 4-acyl-isoquinoline derivative and preparation method and application thereof | 绍兴文理学院 | 2023-10-13 | — | — | CN | claimed |
| CN-111995575-A | Preparation method of quinoline amide compound | 河南农业大学 | 2020-11-27 | — | — | CN | claimed |
| CN-104364235-B | Amide derivatives as TTX-S blockers | 拉夸里亚创药株式会社 | 2017-07-04 | — | — | CN | claimed |
| CN-101781247-B | New method for synthesizing substituted 3-quinoline carboxylic acid and analogue | UNIV SHANGHAI MARITIME | 2013-01-02 | — | — | CN | claimed |
| CN-101781247-A | New method for synthesizing substituted 3-quinoline carboxylic acid and analogue | UNIV SHANGHAI MARITIME | 2010-07-21 | — | — | CN | claimed |
| EP-2073799-A2 | NOVEL AGENTS OF CALCIUM ION CHANNEL MODULATORS | VM Discovery, Inc. (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008112715-A2 | NOVEL AGENTS OF CALCIUM ION CHANNEL MODULATORS | VM DISCOVERY INC. (US) | 2008-09-18 | — | — | WO | claimed |
| US-4673682-A | ANTIARRYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-16 | — | — | US | claimed |
| EP-0105210-B1 | ISOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | claimed |
| EP-4722196-A1 | CRYSTAL OF VIRAL PROTEASE INHIBITOR AND USE | Westlake Pharmaceuticals (Hangzhou) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| EP-3856178-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-11 | — | — | EP | disclosed |
| EP-4695230-A1 | PROTEASE INHIBITORS AND USES THEREOF | Westlake Pharmaceuticals (Hangzhou) Co., Ltd. (CN) | 2026-02-18 | — | — | EP | disclosed |
| US-20250042889-A1 | 3CLPRO PROTEASE INHIBITOR | SHANGHAI QILU PHARMACEUTICAL RESEARCH AND DEVELOPMENT CENTRE LTD. (CN) | 2025-02-06 | — | — | US | disclosed |
| WO-1986000898-A1 | COMPOUNDS FOR SITE-ENHANCED DELIVERY OF RADIONUCLIDES AND USES THEREOF | UNIVERSITY OF FLORIDA (US) | 1986-02-13 | — | — | WO | disclosed |
| US-4540564-A | DIHYDROPYRIDINE AND/OR PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1985-09-10 | — | — | US | disclosed |
| US-4396619-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4382932-A | Isoquinolinium substituted cephalosporins | ELI LILLY AND COMPANY (US) | 1983-05-10 | — | — | US | disclosed |
| US-4137315-A | ANTIMICROBIAL, ANTIFUNGAL, ANTISEPTICS | RHONE-POULENC INDUSTRIES (FR) | 1979-01-30 | — | — | US | disclosed |
| US-4053300-A | BACTERICIDES | PHILAGRO (FR) | 1977-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577243-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, FAAH | NR4A1 722/4885NR4A2 1245/4885NR4A3 652/4885 |
| US-20250042889-A1 | 3CLPRO PROTEASE INHIBITOR | ACE, ACE2, CTRL | NR4A1 2352/4885NR4A2 3381/4885NR4A3 2399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.