Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 9/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16078924 | 0.89 | DPP8 (0.41) | CTSSCTSLTNK2BTKEGLN2 | |
| SCHEMBL17375372 | 0.83 | BTK (0.53) | TNK2BTKEGFRSRC | |
| SCHEMBL25435246 | 0.74 | BTK (0.46) | CTSSCTSLBTKCTSKCTSB | |
| SCHEMBL26534323 | 0.74 | BTK (0.46) | CTSSCTSLBTKCTSKCTSB | |
| SCHEMBL16078942 | 0.73 | BTK (0.53) | TNK2BTKEGFRSRC | |
| SCHEMBL15669624 | 0.70 | BTK (0.56) | BTKEGFRSRC | |
| SCHEMBL724431 | 0.70 | CTSS (0.45) | CTSSCTSLCTSKCTSBHPGD | |
| SCHEMBL727044 | 0.69 | CTSS (0.40) | CTSSCTSLCTSKCTSBHPGD | |
| SCHEMBL728077 | 0.68 | CTSS (0.39) | CTSSCTSLCTSKCTSBHPGD | |
| SCHEMBL5078551 | 0.67 | CTSL (0.59) | CTSSCTSLCTSKDPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376193-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376193-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT | BTK, SYK, JAK2 | CTSS 1892/4885CTSL 956/4885TNK2 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.