Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584947 | 1.00 | TSHR (0.40) | TSHRHPGDMAPTTHRBTHRA | |
| SCHEMBL5358176 | 1.00 | TSHR (0.40) | TSHRHPGDMAPTTHRBTHRA | |
| SCHEMBL5358881 | 1.00 | TSHR (0.40) | TSHRHPGDMAPTTHRBTHRA | |
| SCHEMBL5350733 | 1.00 | TSHR (0.40) | TSHRHPGDMAPTTHRBTHRA | |
| SCHEMBL5354708 | 0.98 | TSHR (0.41) | TSHRHPGDMAPTTHRBTHRA | |
| SCHEMBL4672306 | 0.94 | TSHR (0.45) | TSHRHPGDTHRBTHRAZDHHC20 | |
| SCHEMBL4441183 | 0.88 | TSHR (0.37) | TSHRHPGDTHRB | |
| SCHEMBL27433006 | 0.84 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL5356473 | 0.82 | MAPT (0.33) | MAPTGPR84FFAR1ZDHHC7FAAH | |
| SCHEMBL5356468 | 0.82 | MAPT (0.33) | MAPTGPR84FFAR1ZDHHC7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127421-A1 | POLYURETHANE COPOLYMERS AND BLENDS, METHODS OF MANUFACTURE THEREOF AND ARTICLES CONTAINING THE SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2022-04-28 | — | — | US | disclosed |
| US-10221274-B2 | Polyurethanes, articles comprising the same and methods of manufacture thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170152338-A1 | POLYURETHANES, ARTICLES COMPRISING THE SAME AND METHODS OF MANUFACTURE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-06-01 | — | — | US | disclosed |
| WO-2015200591-A1 | POLYURETHANES, ARTICLES COMPRISING THE SAME AND METHODS OF MANUFACTURE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-12-30 | — | — | WO | disclosed |