Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378347 | 1.00 | KEAP1 (0.39) | KEAP1NFE2L2ROCK2GRK2 | |
| SCHEMBL17378348 | 1.00 | KEAP1 (0.39) | KEAP1NFE2L2ROCK2GRK2 | |
| SCHEMBL18811989 | 0.85 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL17378363 | 0.79 | KEAP1 (0.43) | KEAP1NFE2L2 | |
| SCHEMBL13532040 | 0.79 | KEAP1 (0.55) | KEAP1NFE2L2 | |
| SCHEMBL30892082 | 0.79 | KEAP1 (0.55) | KEAP1NFE2L2 | |
| SCHEMBL19129822 | 0.79 | KEAP1 (0.55) | KEAP1NFE2L2 | |
| SCHEMBL17378352 | 0.77 | KEAP1 (0.43) | KEAP1NFE2L2 | |
| SCHEMBL17378351 | 0.76 | KEAP1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL17378357 | 0.76 | KEAP1 (0.42) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119641-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TopGeniX, Inc. | 2017-05-04 | — | — | US | disclosed |
| US-20170119641-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TopGeniX, Inc. | 2017-05-04 | — | — | US | disclosed |
| WO-2015195546-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TopGeniX, Inc. (US) | 2015-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119641-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | ERCC4, ERCC1, UNG | KEAP1 1046/4885NFE2L2 212/4885ROCK2 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.