Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378347 | 1.00 | KEAP1 (0.39) | KEAP1NFE2L2ROCK2GRK2 | |
| SCHEMBL17378346 | 1.00 | KEAP1 (0.39) | KEAP1NFE2L2ROCK2GRK2 | |
| SCHEMBL18811989 | 0.85 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL17378363 | 0.79 | KEAP1 (0.43) | KEAP1NFE2L2 | |
| SCHEMBL13532040 | 0.79 | KEAP1 (0.55) | KEAP1NFE2L2 | |
| SCHEMBL30892082 | 0.79 | KEAP1 (0.55) | KEAP1NFE2L2 | |
| SCHEMBL19129822 | 0.79 | KEAP1 (0.55) | KEAP1NFE2L2 | |
| SCHEMBL17378352 | 0.77 | KEAP1 (0.43) | KEAP1NFE2L2 | |
| SCHEMBL17378351 | 0.76 | KEAP1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL17378357 | 0.76 | KEAP1 (0.42) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015195546-A1 | TOPICAL FORMULATIONS FOR UV PROTECTION | TopGeniX, Inc. (US) | 2015-12-23 | — | — | WO | disclosed |