SCHEMBL17378554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17378563	0.87	RAB9A (0.45)	KDM4EALDH1A1CYP1A2HPGDKMT2A
	SCHEMBL14504050	0.85	KDM4E (0.46)	KDM4EALDH1A1CYP1A2HPGDKMT2A
	SCHEMBL16595230	0.82	KDM4E (0.42)	KDM4EALDH1A1CYP1A2HPGDKMT2A
	SCHEMBL10238327	0.81	MEN1 (0.47)	KDM4ECYP1A2KMT2APDE2AACSS2
	SCHEMBL26790445	0.80	MAPT (0.49)	ALDH1A1HPGDKMT2APDE2AACSS2
	SCHEMBL5419669	0.80	KDM4E (0.44)	KDM4EALDH1A1HPGDKMT2AACSS2
	SCHEMBL20799418	0.79	AGPAT2 (0.47)	KDM4EALDH1A1CYP1A2HPGDKMT2A
	SCHEMBL13057628	0.79	ACSS2 (0.43)	KDM4ECYP1A2KMT2AACSS2
	SCHEMBL17378608	0.78	FGFR1 (0.42)	KMT2AACSS2HTTFGFR1MAPK14
	SCHEMBL10239601	0.78	ACSS2 (0.63)	KDM4EALDH1A1HPGDKMT2AACSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.