Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.33 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788487 | 1.00 | DDB1 (0.36) | DDB1CRBNNR1H2SLC34A1USP2 | |
| SCHEMBL28037308 | 0.91 | NAMPT (0.37) | DDB1CRBNNR1H2SLC34A1USP2 | |
| SCHEMBL823793 | 0.88 | HDAC1 (0.41) | DDB1CRBNNR1H2SLC34A1NAMPT | |
| SCHEMBL826919 | 0.86 | NAMPT (0.39) | DDB1CRBNNR1H2SLC34A1NAMPT | |
| SCHEMBL20483907 | 0.83 | USP9X (0.38) | NAMPT | |
| SCHEMBL14358443 | 0.80 | HDAC1 (0.40) | DDB1CRBNNR1H2SLC34A1NAMPT | |
| SCHEMBL19203380 | 0.79 | USP2 (0.45) | NR1H2USP2SMN1; SMN2NAMPTRECQL | |
| SCHEMBL17380568 | 0.78 | HDAC1 (0.39) | DDB1CRBNNR1H2SLC34A1NAMPT | |
| SCHEMBL20392817 | 0.74 | HDAC1 (0.44) | DDB1CRBNNR1H2SLC34A1USP2 | |
| SCHEMBL18376191 | 0.74 | NR1H2 (0.46) | DDB1CRBNNR1H2USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121338-A1 | AMINO PRYAN RING DERIVATIVE AND COMPOSITION AND USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD (CN) | 2017-05-04 | — | — | US | disclosed |
| US-20170121338-A1 | AMINO PRYAN RING DERIVATIVE AND COMPOSITION AND USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD (CN) | 2017-05-04 | — | — | US | disclosed |
| US-20170121338-A1 | AMINO PRYAN RING DERIVATIVE AND COMPOSITION AND USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD (CN) | 2017-05-04 | — | — | US | disclosed |
| CN-105518008-A | Amino pyranoid ring derivative and composition and use thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-04-20 | — | — | CN | disclosed |
| WO-2015192701-A1 | AMINO PYRANOID RING DERIVATIVE AND COMPOSITION AND USE THEREOF | 四川海思科制药有限公司 | 2015-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121338-A1 | AMINO PRYAN RING DERIVATIVE AND COMPOSITION AND USE THEREOF | DPP4, DPP8, DPP3 | DDB1 2091/4885CRBN 2487/4885NR1H2 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.