Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788487 | 0.91 | DDB1 (0.36) | NAMPTDDB1CRBNMTORHDAC1 | |
| SCHEMBL17380554 | 0.91 | DDB1 (0.36) | NAMPTDDB1CRBNMTORHDAC1 | |
| SCHEMBL823793 | 0.90 | HDAC1 (0.41) | NAMPTDDB1CRBNHDAC1MAPT | |
| SCHEMBL826919 | 0.87 | NAMPT (0.39) | NAMPTDDB1CRBNHDAC1MAPT | |
| SCHEMBL14358443 | 0.83 | HDAC1 (0.40) | NAMPTDDB1CRBNHDAC1MAPT | |
| SCHEMBL17380568 | 0.81 | HDAC1 (0.39) | NAMPTDDB1CRBNHDAC1MAPT | |
| SCHEMBL20392817 | 0.80 | HDAC1 (0.44) | NAMPTDDB1CRBNMTORHDAC1 | |
| SCHEMBL19203380 | 0.80 | USP2 (0.45) | NAMPTMTORHDAC1PIK3CAMAPT | |
| SCHEMBL21257533 | 0.77 | USP9X (0.46) | NAMPTHDAC1PIK3CANR1H2ESR2 | |
| SCHEMBL22403012 | 0.76 | PDK2 (0.50) | NAMPTDDB1CRBNMTORHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037367-A | Amino six-membered ring derivative and application thereof in medicines | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-11-11 | — | — | CN | disclosed |