Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174062 | 1.00 | HSD11B1 (0.48) | HSD11B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15021866 | 0.85 | HDAC4 (0.51) | HSD11B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL163930 | 0.85 | HDAC4 (0.51) | HSD11B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30584793 | 0.80 | ALDH1A1 (0.56) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL171022 | 0.78 | CA12 (0.56) | HSD11B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL162488 | 0.77 | SCN10A (0.49) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL162574 | 0.77 | SCN10A (0.49) | KDM4EALDH1A1GAALMNATSHR | |
| SCHEMBL4521239 | 0.74 | CYP1A2 (0.66) | HSD11B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4521230 | 0.74 | CYP1A2 (0.66) | HSD11B1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL162177 | 0.74 | S1PR4 (0.49) | KDM4EALDH1A1GAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611783-A2 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS | Piramal Enterprises Limited (IN) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029032-A2 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-03-08 | — | — | WO | disclosed |