Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17383179 | 0.89 | LMNA (0.43) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17382619 | 0.88 | LMNA (0.42) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17383249 | 0.84 | LMNA (0.45) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27148710 | 0.81 | NPC1 (0.36) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27153704 | 0.81 | NPC1 (0.36) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17383248 | 0.80 | LMNA (0.52) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30092787 | 0.80 | CNR2 (0.35) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27140601 | 0.80 | CNR2 (0.35) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL18854934 | 0.79 | — | — | |
| SCHEMBL18866410 | 0.79 | POLB (0.38) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015198859-A1 | CONDENSED HETEROCYCLIC COMPOUND | 住友化学株式会社 | 2015-12-30 | — | — | WO | disclosed |