Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543391 | 0.91 | LMNA (0.35) | LMNAHTTSMN1; SMN2CNR2NPC1 | |
| SCHEMBL27145437 | 0.91 | LMNA (0.35) | LMNAHTTSMN1; SMN2CNR2NPC1 | |
| SCHEMBL29542880 | 0.89 | CNR2 (0.35) | LMNAHTTSMN1; SMN2CNR2NPC1 | |
| SCHEMBL17383123 | 0.88 | DDR1 (0.36) | SMN1; SMN2CNR2ALDH1A1RORCGAA | |
| SCHEMBL17382576 | 0.85 | CA12 (0.32) | CNR2NPC1RAB9ACA12CA9 | |
| SCHEMBL17383192 | 0.85 | CNR2 (0.30) | CNR2NPC1RAB9AALOX5AP | |
| SCHEMBL17383179 | 0.84 | LMNA (0.43) | LMNAHTTSMN1; SMN2CNR2NPC1 | |
| SCHEMBL17949562 | 0.84 | SMN1; SMN2 (0.32) | SMN1; SMN2CNR2NPC1RAB9AHPGD | |
| SCHEMBL17382836 | 0.84 | LMNA (0.43) | LMNAHTTSMN1; SMN2CNR2NPC1 | |
| SCHEMBL17382619 | 0.83 | LMNA (0.42) | LMNAHTTSMN1; SMN2CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015198859-A1 | CONDENSED HETEROCYCLIC COMPOUND | 住友化学株式会社 | 2015-12-30 | — | — | WO | disclosed |