Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 4/20 | 0.52 |
| ▸ | MARS1 | P56192 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738076 | 0.79 | MARS1 (0.64) | RPA1MARS1ALDH1A1MAPTHTT | |
| SCHEMBL3023379 | 0.78 | RAB9A (0.41) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL15964701 | 0.76 | P2RY14 (0.52) | ALDH1A1P2RY14L3MBTL1 | |
| SCHEMBL31429324 | 0.75 | RPA1 (0.54) | RPA1MARS1ALDH1A1MAPTHTT | |
| SCHEMBL12154500 | 0.75 | P2RY14 (0.39) | RPA1MARS1P2RY14 | |
| SCHEMBL20388614 | 0.73 | HTR2C (0.64) | P2RY14 | |
| SCHEMBL21384233 | 0.73 | P2RY14 (0.43) | ALDH1A1MAPTMEN1KMT2AP2RY14 | |
| SCHEMBL18939425 | 0.72 | RPA1 (0.54) | RPA1MARS1ALDH1A1MAPTHTT | |
| SCHEMBL28554732 | 0.72 | MARS1 (0.61) | RPA1MARS1P2RY14 | |
| SCHEMBL3564370 | 0.72 | SMPD1 (0.59) | RPA1MARS1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390252-A1 | New pyrazole derivatives | Almirall, S.A. (ES) | 2011-11-30 | — | — | EP | disclosed |