SCHEMBL17384233

SCHEMBL17384233

O=c1cc(C=Cc2cccc3ccccc23)c2ccccc2o1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NQO1 P15559 1/20 0.49
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA9 Q16790 2/20 0.47
RXRA P19793 1/20 0.44
KDM4E B2RXH2 2/20 0.43
RAB9A P51151 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
CDC25A P30304 1/20 0.43
CDC25C P30307 1/20 0.43
GAA P10253 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17384204 0.83 CDC25A (0.61) ALDH1A1LMNACA12CA1CA9
SCHEMBL17384072 0.83 CDC25A (0.61) ALDH1A1LMNACA12CA1CA9
SCHEMBL17384094 0.82 KMT2A (0.57) ALDH1A1SMN1; SMN2KDM4EMAPTHPGD
SCHEMBL1414225 0.81 ALDH1A1 (0.71) ALDH1A1LMNASMN1; SMN2NQO1CA12
SCHEMBL1414224 0.81 ALDH1A1 (0.71) ALDH1A1LMNASMN1; SMN2NQO1CA12
SCHEMBL28695610 0.79 NQO1 (0.53) ALDH1A1LMNASMN1; SMN2NQO1CA12
SCHEMBL17384212 0.77 CDC25A (0.58) ALDH1A1LMNACA12CA1CA9
SCHEMBL17384098 0.77 CDC25A (0.58) ALDH1A1LMNACA12CA1CA9
SCHEMBL1395382 0.76 NQO1 (0.58) ALDH1A1LMNASMN1; SMN2NQO1CA12
SCHEMBL10706687 0.75 CHAT (0.62) ALDH1A1LMNARXRAKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015199141-A1 COUMALIN-BASED CONDENSED RING COMPOUND EXHIBITING LUMINESCENCE/SEMICONDUCTOR PROPERTIES, AND METHOD FOR MANUFACTURING SAME 国立大学法人 群馬大学 2015-12-30 WO disclosed