SCHEMBL17384261

SCHEMBL17384261

O=C(O)c1ccc(C[n+]2ccc(-c3ccncc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.48
GSK3B P49841 2/20 0.48
ROCK2 O75116 1/20 0.46
RPS6KA5 O75582 1/20 0.46
MAP4K4 O95819 1/20 0.46
PRKCG P05129 1/20 0.46
PRKACA P17612 1/20 0.46
RPS6KB1 P23443 1/20 0.46
MAPK1 P28482 1/20 0.46
AKT1 P31749 1/20 0.46
GSK3A P49840 1/20 0.46
PRKX P51817 1/20 0.46
PRKCD Q05655 1/20 0.46
PRKG2 Q13237 1/20 0.46
ROCK1 Q13464 1/20 0.46
DYRK1A Q13627 1/20 0.46
PRKG1 Q13976 1/20 0.46
PKN2 Q16513 1/20 0.46
CDC42BPA Q5VT25 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13974631 0.90 ALDH1A1 (0.53) ALDH1A1KDM4ERAB9AEPHX2NR1H4
SCHEMBL30672827 0.86 NAPRT (0.43) NAPRTGSK3BROCK2RPS6KA5MAP4K4
SCHEMBL12905317 0.85 ALDH1A1 (0.56) ALDH1A1KDM4ERAB9AEPHX2NR1H4
SCHEMBL16433561 0.85 ALDH1A1 (0.56) ALDH1A1KDM4ERAB9AEPHX2NR1H4
SCHEMBL9999526 0.85 CHKA (0.52) ALDH1A1KDM4ERAB9ACYP17A1CHKA
Bromide SCHEMBL15361681 0.83 CHKA (0.55) ALDH1A1KDM4ERAB9ACHKA
Hydrochloric Acid SCHEMBL28933331 0.81 FOLH1 (0.45) GSK3BROCK2RPS6KA5MAP4K4PRKCG
Hydrochloric Acid SCHEMBL30148005 0.81 FOLH1 (0.45) GSK3BROCK2RPS6KA5MAP4K4PRKCG
Hydrochloric Acid SCHEMBL28933334 0.81 FOLH1 (0.45) GSK3BROCK2RPS6KA5MAP4K4PRKCG
Bromide SCHEMBL15361505 0.81 CHKA (0.58) ALDH1A1KDM4ERAB9ACYP17A1CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658849-A A kind of Cr (III) complex and its preparation method and application 太原师范学院 2018-10-16 CN disclosed
WO-2015193301-A1 AN ELECTROCHROMIC MATERIAL, AND AN ELECTROCHROMIC PARTICLE AND AN ELECTROCHROMIC DEVICE COMPRISING THE SAME IRIDOS LTD. (KR) 2015-12-23 WO disclosed