Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 10/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15361681 | 0.98 | CHKA (0.55) | CHKAKDM4EALDH1A1RAB9APABPC1 | |
| Bromide SCHEMBL15361505 | 0.96 | CHKA (0.58) | CHKAKDM4EALDH1A1RAB9APABPC1 | |
| SCHEMBL23373046 | 0.91 | KDM4E (0.67) | CHKAKDM4EALDH1A1RAB9APABPC1 | |
| SCHEMBL1108062 | 0.91 | ALDH1A1 (0.62) | CHKAKDM4EALDH1A1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL7166354 | 0.90 | ALDH1A1 (0.66) | CHKAKDM4EALDH1A1RAB9APABPC1 | |
| SCHEMBL1108034 | 0.90 | ALDH1A1 (0.66) | CHKAKDM4EALDH1A1RAB9APABPC1 | |
| Hydrochloric Acid SCHEMBL28357009 | 0.88 | ALDH1A1 (0.64) | CHKAKDM4EALDH1A1RAB9APABPC1 | |
| Hydrochloric Acid SCHEMBL27637987 | 0.88 | ALDH1A1 (0.64) | CHKAKDM4EALDH1A1RAB9APABPC1 | |
| Bromide SCHEMBL10969375 | 0.88 | ALDH1A1 (0.64) | CHKAKDM4EALDH1A1RAB9ALMNA | |
| SCHEMBL19646819 | 0.86 | CHKA (0.49) | CHKAKDM4EALDH1A1RAB9APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160223558-A1 | ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES | PORTLAND STATE UNIVERSITY (US) | 2016-08-04 | — | — | US | disclosed |
| US-8927727-B2 | Thiol detection | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2015-01-06 | — | — | US | disclosed |
| WO-2013003812-A2 | ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES | THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2013-01-03 | — | — | WO | disclosed |
| US-20120276649-A1 | THIOL DETECTION | THE OREGON BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY | 2012-11-01 | — | — | US | disclosed |
| US-20120083582-A1 | ELECTRICALLY CONDUCTIVE POLYROTAXANE | NAT'L INSTITUTE FOR MATERIALS SCIENCE (JP) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160223558-A1 | ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES | BLVRB, CBR3, AKR7A2 | CHKA 3565/4885KDM4E 2006/4885ALDH1A1 235/4885 |
| US-20120276649-A1 | THIOL DETECTION | GLO1, AHCY, BHMT2 | CHKA 2980/4885KDM4E 1931/4885ALDH1A1 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.