Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | PLEC | Q15149 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | GNG2 | P59768 | 1/20 | 0.46 |
| ▸ | GNB1 | P62873 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 12/20 | 0.45 |
| ▸ | CA1 | P00915 | 10/20 | 0.45 |
| ▸ | CA2 | P00918 | 10/20 | 0.45 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062763 | 0.89 | USP2 (0.53) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL14093812 | 0.86 | USP2 (0.59) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL13881039 | 0.85 | USP2 (0.64) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL14148863 | 0.84 | USP2 (0.60) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL173061 | 0.84 | USP2 (0.73) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL2790042 | 0.83 | MEN1 (0.68) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL12061907 | 0.83 | USP2 (0.66) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL14252410 | 0.82 | USP2 (0.55) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL13211048 | 0.82 | USP2 (0.55) | USP2MEN1POLBKMT2AATM | |
| SCHEMBL13436012 | 0.82 | USP2 (0.52) | USP2MEN1POLBKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015195240-A1 | GRP78 TARGETED CONJUGATES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2015-12-23 | — | — | WO | disclosed |