SCHEMBL173061

SCHEMBL173061

CC(=O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.73
▸ L3MBTL1 Q9Y468 1/20 0.73
▸ MEN1 O00255 2/20 0.61
▸ POLB P06746 2/20 0.61
▸ KMT2A Q03164 2/20 0.61
▸ ALPL P05186 1/20 0.61
▸ ALPI P09923 1/20 0.61
▸ ALPG P10696 1/20 0.61
▸ ATM Q13315 1/20 0.60
▸ PLEC Q15149 1/20 0.60
▸ CA9 Q16790 14/20 0.59
▸ CA1 P00915 12/20 0.59
▸ CA2 P00918 12/20 0.59
▸ CA12 O43570 4/20 0.56
▸ DNASE1L3 Q13609 1/20 0.55
▸ PRMT1 Q99873 1/20 0.55
▸ ESR1 P03372 1/20 0.54
▸ CA14 Q9ULX7 2/20 0.53
▸ CA7 P43166 2/20 0.52
▸ ALB P02768 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12061907 0.93 USP2 (0.66) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL1437042 0.92 USP2 (0.78) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL10142506 0.91 USP2 (0.67) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL12463125 0.89 USP2 (0.77) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL19423916 0.89 USP2 (0.73) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL19449068 0.89 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL10138306 0.89 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL19543669 0.89 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14563221 0.89 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20990646 0.87 USP2 (0.67) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3294811-B1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY GROUP CORP (JP) 2024-02-28 — — EP disclosed
EP-3737418-B1 POLYMERS WITH RIGID SPACING GROUPS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS SONY GROUP CORP (JP) 2024-02-28 — — EP disclosed
EP-3455299-B1 COMPOSITIONS COMPRISING A POLYMERIC DYE AND A CYCLODEXTRIN AND USES THEREOF SONY GROUP CORP (JP) 2024-01-17 — — EP disclosed
WO-2023242661-A2 POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-12-21 — — WO disclosed
WO-2023242662-A2 POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-12-21 — — WO disclosed
EP-4234689-A2 SPLIT INTEINS WITH EXCEPTIONAL SPLICING ACTIVITY The Trustees of Princeton University (US) 2023-08-30 — — EP disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
EP-3408292-B1 SPLIT INTEINS WITH EXCEPTIONAL SPLICING ACTIVITY UNIV PRINCETON (US) 2023-04-26 — — EP disclosed
EP-4137818-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS Sony Group Corporation (JP) 2023-02-22 — — EP disclosed
US-20220220314-A1 POLYMERIC DYES WITH LINKER GROUPS COMPRISING DEOXYRIBOSE Sony Group Corporation (JP) 2022-07-14 — — US disclosed
US-8835480-B2 Inhibitors for steroid response elements and related methods CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-09-16 — — US disclosed
US-20120058932-A1 ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION MAX PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2012-03-08 — — US disclosed
US-7923433-B2 Activity-based probes and methods of their preparation and use ACTIVX BIOSCIENCES, INC. (US) 2011-04-12 — — US disclosed
US-7923433-B2 Activity-based probes and methods of their preparation and use ACTIVX BIOSCIENCES, INC. (US) 2011-04-12 — — US disclosed
EP-2230314-A1 Method of sensing an analyte The Board of Regents,The University of Texas System (US) 2010-09-22 — — EP disclosed
US-7365178-B2 Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis ACTIVX BIOSCIENCES, INC. (US) 2008-04-29 — — US disclosed
US-7365178-B2 Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis ACTIVX BIOSCIENCES, INC. (US) 2008-04-29 — — US disclosed
US-7256019-B2 Terminal phosphate blocked nucleoside polyphosphates GE HEALTHCARE BIO-SCIENCES CORP. (US) 2007-08-14 — — US disclosed
US-20070141624-A1 ACTIVITY-BASED PROBES AND METHODS OF THEIR PREPARATION ANS USE ACTIVX BIOSCIENCES, INC. 2007-06-21 — — US disclosed
US-20070141624-A1 ACTIVITY-BASED PROBES AND METHODS OF THEIR PREPARATION ANS USE ACTIVX BIOSCIENCES, INC. 2007-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070141624-A1 ACTIVITY-BASED PROBES AND METHODS OF THEIR PREPARATION ANS USE DNPEP, CTRL, ARSA USP2 157/4885L3MBTL1 2196/4885MEN1 4670/4885
US-20220220314-A1 POLYMERIC DYES WITH LINKER GROUPS COMPRISING DEOXYRIBOSE H1-0, POLM, H1-2 USP2 3575/4885L3MBTL1 7/4885MEN1 787/4885
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 USP2 699/4885L3MBTL1 27/4885MEN1 1209/4885
US-20120058932-A1 ACTIVE INGREDIENT-PEPTIDE CONSTRUCT FOR EXTRACELLULAR CONCENTRATION VIP, FIBP, MMP7 USP2 4261/4885L3MBTL1 4427/4885MEN1 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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