Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 6/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.34 |
| ▸ | PIK3R5 | Q8WYR1 | 6/20 | 0.34 |
| ▸ | PIK3R3 | Q92569 | 6/20 | 0.34 |
| ▸ | UGCG | Q16739 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17385443 | 0.89 | UGCG (0.33) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL17381996 | 0.81 | CCNA2 (0.46) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL30885924 | 0.79 | GRM5 (0.37) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL17375078 | 0.78 | PIK3CD (0.31) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL30886147 | 0.78 | GRM5 (0.35) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29538914 | 0.78 | PIK3CD (0.31) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL17783226 | 0.78 | PIK3CD (0.36) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL17385442 | 0.78 | CCNA2 (0.49) | KDM4EKMT2ACCNA2CDK2CCNA1 | |
| SCHEMBL30886207 | 0.74 | — | — | |
| SCHEMBL17375050 | 0.74 | UGCG (0.32) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015196335-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | TOCOPHERX, INC. (US) | 2015-12-30 | — | — | WO | disclosed |