Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17385323 | 0.92 | ALDH1A1 (0.51) | CCNA2CDK2CCNA1ALDH1A1NPSR1 | |
| SCHEMBL17381607 | 0.91 | CCNA2 (0.43) | CCNA2CDK2CCNA1ALDH1A1NPSR1 | |
| SCHEMBL29538955 | 0.91 | CCNA2 (0.43) | CCNA2CDK2CCNA1ALDH1A1NPSR1 | |
| SCHEMBL30885867 | 0.90 | CCNA2 (0.43) | CCNA2CDK2CCNA1ALDH1A1NPSR1 | |
| SCHEMBL16377773 | 0.88 | CCNA2 (0.43) | CCNA2CDK2CCNA1ALDH1A1NPSR1 | |
| SCHEMBL17381996 | 0.88 | CCNA2 (0.46) | CCNA2CDK2CCNA1ALDH1A1TP53 | |
| SCHEMBL16377789 | 0.84 | TP53 (0.40) | CCNA2CDK2CCNA1ALDH1A1NPSR1 | |
| SCHEMBL16377845 | 0.82 | CCNA2 (0.38) | CCNA2CDK2CCNA1ALDH1A1NPSR1 | |
| SCHEMBL17385521 | 0.81 | L3MBTL1 (0.42) | CCNA2CDK2CCNA1ALDH1A1NPSR1 | |
| SCHEMBL30885869 | 0.78 | CCNA2 (0.39) | CCNA2CDK2CCNA1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015196335-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | TOCOPHERX, INC. (US) | 2015-12-30 | — | — | WO | disclosed |