SCHEMBL1738846

SCHEMBL1738846

C#CCn1c(C)c(C)c2ccnc(-c3ccc(C=C)cc3)c21

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
CACNA1B Q00975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1736308 0.99 ACHE (0.35) ACHECACNA1B
SCHEMBL1737399 0.87 ACHE (0.39) ACHE
Hydrochloric Acid SCHEMBL1737857 0.85 ACHE (0.38) ACHE
SCHEMBL1737960 0.85 CACNA1B (0.35) CACNA1B
Hydrochloric Acid SCHEMBL1736808 0.84 CACNA1B (0.34) CACNA1B
SCHEMBL1737486 0.84 CACNA1B (0.34) CACNA1B
SCHEMBL1738139 0.84 ACHE (0.37) ACHE
SCHEMBL1736111 0.84 ACHE (0.37) ACHE
SCHEMBL1738709 0.83 CACNA1B (0.34) CACNA1B
Hydrochloric Acid SCHEMBL1735787 0.83 ACHE (0.37) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-A4 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-09-09 EP claimed
JP-2008511621-A 2008-04-17 JP claimed
EP-1784404-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 EP claimed
WO-2006025716-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed