Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17388709 | 0.89 | NR1H4 (0.52) | GPBAR1HSD11B1 | |
| SCHEMBL15994309 | 0.89 | NR1H4 (0.52) | GPBAR1HSD11B1 | |
| SCHEMBL3781851 | 0.82 | GPBAR1 (0.84) | GPBAR1 | |
| SCHEMBL18799024 | 0.82 | GPBAR1 (0.84) | GPBAR1 | |
| SCHEMBL12447370 | 0.82 | GPBAR1 (0.62) | GPBAR1 | |
| SCHEMBL13129193 | 0.82 | GPBAR1 (0.62) | GPBAR1 | |
| SCHEMBL13165683 | 0.82 | GPBAR1 (0.62) | GPBAR1 | |
| SCHEMBL13806590 | 0.82 | GPBAR1 (0.62) | GPBAR1 | |
| SCHEMBL3788023 | 0.81 | GPBAR1 (0.72) | GPBAR1 | |
| SCHEMBL15362556 | 0.81 | GPBAR1 (0.71) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | MMP8, GUSB, MMP9 | PTPN1 4369/4885GPBAR1 2853/4885HSD11B1 1144/4885 |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | PTPN1 4369/4885GPBAR1 2853/4885HSD11B1 1144/4885 |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | PTPN1 4369/4885GPBAR1 2853/4885HSD11B1 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.