Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1738165 | 0.99 | MCL1 (0.36) | MCL1DYRK1AADORA2AADORA2BCCNA2 | |
| SCHEMBL1737676 | 0.89 | ALDH1A1 (0.39) | DYRK1ACCNA2CDK2ESR1SREBF2 | |
| SCHEMBL1737627 | 0.89 | MAPK14 (0.42) | MCL1DYRK1AMAPTMAPK13MAPK12 | |
| SCHEMBL1736374 | 0.89 | ADORA2B (0.39) | MCL1DYRK1AADORA2AADORA2BCCNA2 | |
| SCHEMBL1737146 | 0.89 | MCL1 (0.38) | MCL1DYRK1ACCNA2CDK2MAPT | |
| Hydrochloric Acid SCHEMBL1736543 | 0.88 | MAPK14 (0.42) | MCL1DYRK1AMAPTMAPK13MAPK12 | |
| Hydrochloric Acid SCHEMBL1736650 | 0.88 | ALDH1A1 (0.38) | DYRK1ACCNA2CDK2ESR1SREBF2 | |
| Hydrochloric Acid SCHEMBL1735622 | 0.88 | ADORA2B (0.38) | MCL1DYRK1AADORA2AADORA2BCCNA2 | |
| Hydrochloric Acid SCHEMBL1738501 | 0.87 | MCL1 (0.38) | MCL1DYRK1ACCNA2CDK2MAPT | |
| SCHEMBL1738000 | 0.87 | DYRK1A (0.49) | DYRK1AADORA2AADORA2BCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |