SCHEMBL1739162

SCHEMBL1739162

COCCn1c(C)c(C)c2ccnc(-c3ccccc3)c21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.44
HPGD P15428 4/20 0.44
LMNA P02545 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
NR2F2 P24468 1/20 0.42
CYP1A2 P05177 10/20 0.41
HSD17B10 Q99714 8/20 0.41
CYP3A4 P08684 7/20 0.41
CYP2C9 P11712 7/20 0.41
TSHR P16473 7/20 0.39
CASP1 P29466 6/20 0.39
CASP7 P55210 6/20 0.39
GLA P06280 3/20 0.39
CYP2C19 P33261 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP2D6 P10635 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1735642 0.99 ALDH1A1 (0.43) ALDH1A1HPGDLMNATDP1KMT2A
SCHEMBL1736932 0.90 KMT2A (0.39) ALDH1A1HPGDLMNATDP1KMT2A
Hydrochloric Acid SCHEMBL1736659 0.89 KMT2A (0.38) ALDH1A1HPGDLMNATDP1KMT2A
SCHEMBL1738099 0.88 ALOX15 (0.47) ALDH1A1HPGDLMNATDP1KMT2A
SCHEMBL1738547 0.88 ALDH1A1 (0.43) ALDH1A1HPGDLMNAKMT2AMEN1
SCHEMBL1737010 0.88 CYP1A2 (0.43) ALDH1A1HPGDKMT2AMEN1CYP1A2
SCHEMBL1735930 0.87 KDM4E (0.42) ALDH1A1LMNANPC1RAB9AHSD17B10
Hydrochloric Acid SCHEMBL1737922 0.86 ALDH1A1 (0.43) ALDH1A1HPGDLMNAKMT2AMEN1
Hydrochloric Acid SCHEMBL1737896 0.86 CYP1A2 (0.43) ALDH1A1HPGDKMT2AMEN1CYP1A2
Hydrochloric Acid SCHEMBL1736625 0.86 ALOX15 (0.46) ALDH1A1HPGDLMNATDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-A4 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-09-09 EP claimed
JP-2008511621-A 2008-04-17 JP claimed
EP-1784404-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 EP claimed
WO-2006025716-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed