SCHEMBL173918

SCHEMBL173918

CC(=O)OC(O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.51
SRC P12931 1/20 0.47
ELANE P08246 1/20 0.41
CES2 O00748 2/20 0.39
KCNN4 O15554 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
TSHR P16473 3/20 0.38
ALDH1A1 P00352 4/20 0.38
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
F2 P00734 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
DAO P14920 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11101775 0.85 CES1 (0.53) CES1SRCCES2KCNN4CYP2C19
SCHEMBL6445934 0.83 CES1 (0.46) CES1SRCELANECES2KCNN4
SCHEMBL14800032 0.83 CYP1A2 (0.44) CES1ELANEKCNN4CYP2C19HIF1A
SCHEMBL5171119 0.83 CYP1A2 (0.44) CES1ELANEKCNN4CYP2C19HIF1A
SCHEMBL1354212 0.83 CYP1A2 (0.44) CES1ELANEKCNN4CYP2C19HIF1A
SCHEMBL2814807 0.82 CES1 (0.51) CES1SRCELANEKCNN4CYP2C19
SCHEMBL277653 0.81 CES1 (0.65) CES1SRCCES2KCNN4CYP2C19
SCHEMBL7154819 0.80 KCNN4 (0.40) CES1SRCELANEKCNN4CYP2C19
Methoxymethane SCHEMBL36163 0.80 CES1 (0.62) CES1SRCCES2KCNN4CYP2C19
SCHEMBL621110 0.79 CES1 (0.52) CES1SRCELANECES2KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108676063-A A kind of double acyloxy bisamide class pharmaceutical intermediates of hydroxyl and preparation method thereof 三峡大学 2018-10-19 CN claimed
CN-103228609-B Method for producing acyloxybenzoic acids WEIR CHEMICAL SWITZERLAND LTD 2015-01-07 CN claimed
US-5039717-A Injection molding cookwear AMOCO CORPORATION (US) 1991-08-13 US claimed
WO-2025072686-A1 KRAS G12D MUTATION TARGETING COMPOUNDS SUMMIT THERAPEUTICS INC. (US) 2025-04-03 WO disclosed
WO-2025059556-A1 COMPOSITIONS COMPRISING PRALATREXATE FOR SUBCUTANEOUS ADMINISTRATION AND METHODS OF USE THEREOF Acrotech Biopharma Inc. (US) 2025-03-20 WO disclosed
EP-4333903-A1 COMPOSITIONS AND METHODS RELATED TO THE TREATMENT OF OCULAR DISEASES IN EQUINES North Carolina State University (US) 2024-03-13 EP disclosed
WO-2023281272-A1 NASAL SPRAY Pollinner Limited (GB) 2023-01-12 WO disclosed
WO-2023278827-A1 3-IODOPROPYL-1,2,3-TRIAZOL-1-YL, 3-BROMOPROPYL-1,2,3-TRIAZOL-1-YL, AND DERIVATIVES FOR USES IN LABELING EMORY UNIVERSITY (US) 2023-01-05 WO disclosed
WO-2022235566-A1 COMPOSITIONS AND METHODS RELATED TO THE TREATMENT OF OCULAR DISEASES IN EQUINES NORTH CAROLINA STATE UNIVERSITY (US) 2022-11-10 WO disclosed
EP-2599830-B2 VINYL-CHLORIDE-BASED RESIN COMPOSITION FOR TRANSPARENT PRODUCT ADEKA CORP (JP) 2022-09-28 EP disclosed
EP-3986879-A1 FUSED 1,2 THIAZOLES AND 1,2 THIAZINES WHICH ACT AS NL3P3 MODULATORS AC Immune SA (CH) 2022-04-27 EP disclosed
EP-0330788-A1 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmia MERRELL DOW PHARMACEUTICALS INC. (US) 1989-09-06 EP disclosed
EP-0330824-A1 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmias MERRELL DOW PHARMACEUTICALS INC. (US) 1989-09-06 EP disclosed
EP-0329905-A1 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for increasing gastric motility MERRELL DOW PHARMACEUTICALS INC. (US) 1989-08-30 EP disclosed
EP-0329903-A1 Use of quinolizinone and quinolizine derivatives in the manufacture of medicaments for the treatment of glaucoma MERRELL DOW PHARMACEUTICALS INC. (US) 1989-08-30 EP disclosed
EP-0329904-A1 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of anxiety MERRELL DOW PHARMACEUTICALS INC. (US) 1989-08-30 EP disclosed
EP-0329932-A2 Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments MERRELL PHARMACEUTICALS INC. (US) 1989-08-30 EP disclosed
EP-0284256-A1 Benzodiazepine analogs MERCK & CO. INC. (US) 1988-09-28 EP disclosed
EP-0099080-B1 SUBSTITUTED TETRAHYDROTETRAZOLO(5,1-A)PHTHALAZINES THE DOW CHEMICAL COMPANY (US) 1988-02-03 EP disclosed
US-4021565-A Process for the alleviation of depression by administration of non-addicting meperidine analogues BERGER FRANK M 1977-05-03 US disclosed