SCHEMBL277653

SCHEMBL277653

COC(O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.65
SRC P12931 1/20 0.55
KCNN4 O15554 1/20 0.46
TSHR P16473 3/20 0.45
CES2 O00748 3/20 0.40
TDP1 Q9NUW8 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 2/20 0.39
F2 P00734 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 1/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
MAPK1 P28482 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL36163 0.98 CES1 (0.62) CES1SRCKCNN4TSHRCES2
Ether SCHEMBL11039163 0.90 CES1 (0.54) CES1SRCKCNN4TSHRCES2
SCHEMBL11101775 0.84 CES1 (0.53) CES1SRCKCNN4TSHRCES2
SCHEMBL621110 0.82 CES1 (0.52) CES1SRCKCNN4TSHRCES2
SCHEMBL11072129 0.82 CES1 (0.53) CES1SRCKCNN4TSHRCES2
SCHEMBL8036600 0.82 KCNN4 (0.50) CES1SRCKCNN4TSHRALDH1A1
SCHEMBL3700347 0.82 KCNN4 (0.50) CES1SRCKCNN4TSHRALDH1A1
SCHEMBL2814807 0.81 CES1 (0.51) CES1SRCKCNN4TSHRTDP1
SCHEMBL173918 0.81 CES1 (0.51) CES1SRCKCNN4TSHRCES2
SCHEMBL11040574 0.81 CES1 (0.51) CES1SRCKCNN4TSHRCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106496030-A Preparation method and applications of the cigarette with latent perfume monomer p-Methoxybenzoic acid esters 湖北中烟工业有限责任公司 2017-03-15 CN claimed
EP-3041627-A1 METAL SINTERING FILM COMPOSITIONS Henkel IP & Holding GmbH (DE) 2016-07-13 EP claimed
CN-1678325-A Sapogenin derivatives, their synthesis and use and method based upon the use PHYTOTECH LTD (GB) 2005-10-05 CN claimed
EP-0516375-B1 Thermosetting powder coating composition ROHM & HAAS (US) 1995-02-08 EP claimed
US-5344353-A Method for manufacturing a cathode ray tube using a film layer composition SAMSUNG ELECTRON DEVICES CO., LTD. (KR) 1994-09-06 US claimed
US-5331103-A Reaction with hydrogen peroxide, hydroquinone from phenol RHONE-POULENC CHIMIE (FR) 1994-07-19 US claimed
US-5266657-A Polyester, hydroxyalkylamide curing agent ROHM AND HAAS COMPANY (US) 1993-11-30 US claimed
EP-0516375-A2 Thermosetting powder coating composition ROHM AND HAAS COMPANY (US) 1992-12-02 EP claimed
EP-0067964-B1 PROCESS FOR THE PREPARATION OF 2-ISOSORBIDE NITRATE Heinrich Mack Nachf. (DE) 1985-04-03 EP claimed
US-12036206-B2 Compositions and methods for pain relief CROSS III WILLIAM H (US) 2024-07-16 US disclosed
CN-117813552-A Photosensitive composition for pattern formation and flexographic plate 日本瑞翁株式会社 2024-04-02 CN disclosed
US-20240041054-A1 ROSA CANINA ROSEHIP UNIVERSITA' DEGLI STUDI DI CAGLIARI (IT) 2024-02-08 US disclosed
CN-115190892-B High molecular weight acrylic triblock copolymer and adhesive composition containing the same 株式会社可乐丽 2024-01-30 CN disclosed
EP-4294361-A1 ROSEHIP UNIVERSITA' DEGLI STUDI DI CAGLIARI (IT) 2023-12-27 EP disclosed
US-4195129-A Method for immobilizing enzymes and microbial cells KANSAI PAINT CO., LTD. (JP) 1980-03-25 US disclosed
US-4144156-A Manufacture of unsymmetric monoacetals of aromatic 1,2-diketones employable as photoiniatiators BASF AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4116965-A STYRYL DYESTUFFS CONTAINING CERTAIN AMINO, CYANOPYRIDINE MOIETIES CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4061834-A NITROMETHANE OR ACETONITRILE SOLVENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1977-12-06 US disclosed
US-4007209-A OF BENZOINS BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-02-08 US disclosed
US-3972928-A Regulating plant growth with quaternary phosphonium aliphatic carboxamide salts BAYCHEM CORPORATION (US) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036206-B2 Compositions and methods for pain relief CBS, CTH, CPT1B CES1 635/4885SRC 2971/4885KCNN4 1960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.